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The first clinical trial on DPP-4 inhibitors was published in 2002, and subsequent randomized controlled trials (RCTs) demonstrated their efficacy, safety, and tolerability (15, 17)
PMID 12218053
Just 6.5% of participants in the Wegovy group experienced a heart event versus 8% in the placebo group
This was confirmed and elaborated on by Fafula, Roman V et al who published research in the Journal of Human Reproductive Sciences that shows glutathione not only important in protecting the sperm and improving motility and viability, but that the female reproductive tract contains extracellular glutathione, and if levels are adequate, would give sperm a survival advantage
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