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Instead of asking whether GLP-1 medications work, clinicians are beginning to ask for whom they work best and what alternative pathways should be considered when responses are incomplete. We asked our experts to explain why GLP-1s dont always work for weight loss and what alternatives are available
As more become available, its becoming more common for people to switch weight loss treatments, but youll always need to do so under the supervision of your clinician
Our analysis indicates that there is no significant influence from unmeasured confounding variables (E-values for the point estimates [lower limits of the CI] were 2.90 [3.32), 1.54 [1.92), and 2.09 [2.39) for mortality, MACE, and MAKE, respectively)
