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Psychological factors influence real-world outcomes even when pharmacological mechanisms are superior
The safety profile for tirzepatide was generally comparable to both liraglutide 3 mg and semaglutide 2.4 mg
Decreases muscle damage by protecting the integrity of the muscle tissue, preserving the contractible function
Study designs to investigate causality rigorously Prospective new-user cohort with active comparator + Recruit new semaglutide users and matched new users of a comparator second-line diabetes therapy with lower genital infection confounding (e.g., DPP4 inhibitor), stratified by menopausal status and baseline GSM
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