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By simultaneously targeting multiple hormonal pathways, it offers a comprehensive approach to diabetes management

On TikTok, Reddit, and some telehealth websites, microdosing glucagon-like peptide-1 (GLP-1) receptor agonist medications is pitched as a gentler, more flexible way to use drugs such as the GLP-1 agonist semaglutide (Ozempic, Wegovy), the dual GIP/GLP-1 agonist tirzepatide (Mounjaro, Zepbound), and oral nonpeptide GLP-1 receptor agonist orforglipron (Foundayo)

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found that tirzepatide led to significant dose-dependent reductions in HbA1c levels when compared to a placebo, once-weekly GLP-1RAs, and basal insulin regimens