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10.1038/nature18309 81 PetraC

Mechanisms of Action The mechanistic basis of BPC-157 activity has been investigated across hundreds of studies using both in vitro cell culture systems and in vivo animal models

[4] As a research-grade lyophilized peptide, BPC-157 should be handled according to batch-specific supplier documentation, institutional laboratory procedures, and standard peptide-handling practice

It was found that 48-h exposure to rotenone significantly increased Ca 2+ content, indicated by Fluo3(i) fluorescence, and increased ceramide content, decreased cell size measured as FSC, and increased annexin V binding