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It targets GLP-1, GIP, and adds the Glucagon Receptor into the mix: The Glucagon Element: While GLP-1 and GIP primarily focus on calorie restriction, satiety, and insulin management, glucagon directly influences energy expenditure
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To elucidate the protective effect of sitagliptin (i.e., the specificity of DDP4 inhibitor) on N2a cells, the experimental study was categorized into four groups: Na2 cell only (i.e., control group) (group I), N2a cell treated by H 2 O 2 (group II), N2a cell treated by H 2 O 2 and sitagliptin (group III), N2a cell + H 2 O 2 + sitagliptin + LY-294002 (i.e., a specific PI3K inhibitor) (group IV)
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