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In the Phase 2 trial, the most commonly reported adverse events were gastrointestinal in nature including nausea, vomiting, diarrhoea, and constipation consistent with the side effect profile seen with other GLP-1-based therapies

An analysis published earlier this year found that patients taking GLP-1 medications experienced lower rates of alcohol use disorder and other substance use disorders than similar patients taking other diabetes medications, prompting researchers to further investigate the drugs potential

Health plans and pharmacy benefit managers that manage drug costs say specialty drugs now account for 50% or greater of the total prescription spending they manage

The FDA has explicitly stated that a "research use only" label does not exempt a product from FDA requirements when the product is marketed or intended for human use [14][15]