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In addition, the data we have from members who have already discontinued a GLP-1 strongly suggests that when the cost (literal and figurative) outweighs the perceived benefit, patients opt out
Read review Dihexa for ME/CFS (Myalgic Encephalomyelitis) DecodeME GWAS preprint Aug 2025 (8 loci, female-only signal), UK ME/CFS Delivery Plan My Full Reality July 2025, NIH Walitt 2024 deep-phenotyping, UBC Nacul LDN trial, NICE NG206, and the ~250,000 UK ME/CFS population
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![Efficacy of tirzepatide in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1](https://www.researchgate.net/publication/363201315/figure/fig3/AS:11431281082605778@1662084799021/Efficacy-of-tirzepatide-in-phase-2-GPGB-14-and-phase-3-SURPASS-1-to-5-15-19.png)
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