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Ahern TH, Young LJ (2009b)
Oral semaglutide (Rybelsus) requires special consideration, as it must also be taken on an empty stomach and can increase thyroxine exposure when coadministered with levothyroxine, potentially necessitating dose adjustments and careful TSH monitoring
The Phase 2 trial used subcutaneous injection into the abdomen, thigh, or upper arm on a rotating basis to minimize local reactions
Breastfeeding Considerations No data exists on Retatrutide excretion into breast milk
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