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[2] [3] Additional important safety considerations include risk of pancreatitis (discontinue if suspected), gallbladder disease, acute kidney injury from dehydration during severe gastrointestinal adverse events, and potential diabetic retinopathy complications in patients with a history of retinopathy
Renal impairment GLP-1 RAs are generally safe in patients with CKD and have demonstrated nephroprotective effects in the FLOW trial, where semaglutide significantly reduced the composite renal endpoint (hospitalization for acute kidney injury, sustained 50% decline in estimated glomerular filtration rate (eGFR), end-stage kidney disease, or renal death) in patients with type 2 diabetes and CKD [15]
That monitoring process and the costs associated are HSA and FSA-eligible
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