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Over CNS, the direct action on NTS, hypothalamic arcuate and surrounding structures, as well as the effect on the ventral tegmental area and nucleus accumbens may act on homeostatic and hedonic hunger, changing palatability and reward behavior
Because of these variables, patience and consistency are key
Jaja SI, Ogungbemi SI, Kehinde MO
Sustained Signaling Kinetics: Pharmacokinetic data suggest prolonged receptor interaction, supporting ongoing signaling effects in preclinical models
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