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It was frequently used in Canada by pharmacies during the COVID-19 pandemic when manufactured supplies of childrens pain medications were in short supply, but the pharmaceutical components to mix those medications were still available in some pharmacies

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The active ingredients used, semaglutide and tirzepatide, are the same active ingredients found in several FDA-approved products, but the compounded formulations themselves have not been reviewed by the FDA for safety, effectiveness, or manufacturing quality

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