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Spotlight on iron and ferroptosis: research progress in diabetic retinopathy

Busse*, Nizar Jarjour, Ronald Sorkness, Sean Fain, and Gina Crisafi

Future Perspectives The scientific studies on seleno-GPxs have so far led to the understanding that the physiological role of seleno-GPxs is not only limited to detoxification of peroxides, but also involves regulating signaling pathways (such as chromatin remodulating, NF-B activation, insulin signaling, mitochondrial integrity, and ferroptosis, among others) [1, 8,9,10]

However, produced by unregulated compounding companies (the so-called gray market, and mainly originating from China), there is no guarantee that the purchased product even contains BPC 157, let alone other contaminants that might cause allergic or other adverse reactions