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in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )
The PCAC meeting, including testimony from key opinion leaders, physicians, and pharmacists, did not create these expectations
And the reverse is true: chronic stress and depression can physically affect the brains structure, especially in older adults
Gu ZY, Liu TQ, Liu C, Yang YN, Tang J, Song H, Wang Y, Yang Y, Yu CZ
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