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Indeed, flow cytometric evaluation of resting B6 MZB confirmed increased phosphorylation of both mTOR and its canonical target S6 (Fig
Transient receptor potential melastatin 5 (TRPM5) KO (B6;129- Trpm 5tm1Csz/J) mice were obtained from Jackson Laboratory ( Heterozygous Trpm5 +/ mice were bred to obtain age- and sex-matched homozygous wild-type (WT) and homozygous Trpm5 / mice
Although both of these index SNPs were in moderate linkage disequilibrium with the BMI-loss coding variant (rs11760106 versus rs10305420 r 2 = 0.57
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