[] Insulin, for instance, requires multiple daily injections, which can be challenging for patients, [] and while metformin is generally well-tolerated, its safety profile remains somewhat controversial, as it crosses the placenta
The 2006 human study that Protandim quoted above is only a half-truth: yes, there was a 40% decrease in oxidative stress in study subjects using the TBARS test (which is not considered to be a reliable marker.) The methodology was also a mess
In addition, existing imaging techniques for EAT assessment lack unified standards and specifications regarding the accuracy of EAT volume measurement, the precision of density analysis, and the comprehensiveness of functional evaluation
Conclusion The present review has summarized the current clinical evidence for a potential use of GLP-1R agonists in prospective neuroprotective treatment strategies against glaucoma and other neurodegenerative diseases