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These are some signs that protein intake on semaglutide or other GLP-1 medications may be insufficient: Physical signs: Noticeable loss of muscle tone or physical strength, increased fatigue with normal activity, slower recovery after exercise, hair thinning or increased shedding, feeling weak or unsteady

Monitoring: Clinicians typically track melatonin rhythm, cortisol patterns, inflammatory markers (hs-CRP), and in some cases, telomere length via commercial testing as a baseline and follow-up tool

95% confidence interval [CI], 1.04 to 2.74) [11]