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Both medications accumulate to steady state within 3-4 weeks of consistent weekly injections, though tirzepatide's slightly shorter half-life means it clears more rapidly if doses are delayed
drugs that hitchhike on it stay in circulation far longer
According to current guidelines, asymptomatic gallstones generally do not require intervention, and decisions should be individualized based on symptoms and overall clinical picture
Gastric electrical stimulation (the Enterra device) is FDA-approved under humanitarian device exemption but shows mixed results in clinical trials (McCallum et al., Gastroenterology, 2010)
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