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It helps protect nerves due to its antioxidant properties and the ability to increase acetylcholine production [2]
In our future work, we will examine the comparative effectiveness of alternative treatment options for obesity in patients who discontinue semaglutide or tirzepatide, to help patients and their clinicians make informed decisions. In the obese group, the average body weight lost before discontinuation was 8.4%, with a regain rate of 0.5% one year later
In one study, participants who took Semaglutide lost an average of 15% of their body weight over 68 weeks
[2] [3] NICE guidance (NG28) recommends GLP-1 receptor agonists for adults with type 2 diabetes who have inadequate glycaemic control despite optimal management with metformin and other oral agents, particularly when significant weight loss would be beneficial
