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This happens through the induction of telomerase enzyme activity, resulting in the extension of telomere length
In addition, HDACi promotes the degradation of ECM by regulating the activity of matrix metalloproteinases (MMPs), thereby attenuating the interaction between tumor cells and the stroma and further inhibiting tumor metastasis ( 2.2 Effect of HDACi on macrophages The role of HDACi in regulating the tumor microenvironment is receiving increasing attention, particularly its impact on tumor-associated macrophages
The peptide appears to interact with systems involved in tissue repair
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