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TRT and Heart Health: What the FDA Updated in February 2025 For years, testosterone products carried a cardiovascular black-box warning the most serious warning category the FDA applies to medications
Unknown Long-Term Effects Some novel or less-studied peptides (for instance, KPV peptide side effects or MOTS-c peptide side effects ) may lack extensive long-term safety data
The main gaps concern long-term use in larger and more diverse patient populations over longer periods
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