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Glossary References 1 AbdelN.AtiaG.ShalabyH

Research applications for TB-500 include: Skeletal muscle fiber regeneration Chemotaxis of myoblasts, the precursor cells involved in muscle repair Systemic anti-inflammatory modulation Wound healing across skin and connective tissue Because TB-500 circulates systemically after administration, preclinical models suggest it can reach multiple injury sites at once rather than acting only where it is applied

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This approach is mainly indicated for lesions involving less than 90 of the bowel circumference and 3 cm in length (with double discoid excision feasible for larger lesions ~5 cm), aiming to reduce morbidity compared to segmental resection while maintaining similar recurrence rates