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In the following section, we translate these mechanistic findings into clinical applications, evaluating emerging strategiesincluding ferroptosis inhibitors, iron chelation therapies, and biomarker-driven approachesdesigned to disrupt this pathological cycle and modify the progression of COPD

For the majority of people, folic acid effectively supports one-carbon metabolism and lowers homocysteine, while methylfolate may provide additional benefit in specific clinical or genetic circumstances

THE EMBO JOURNAL

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