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Following this exploratory 12-week pilot study, a randomised, double-blind trial with direct or indirect intracranial pressure measurement is now being planned by the same research team in Naples, led by professor Roberto De Simone
As adoption increases, so does the potential impact on category performance, portfolio strategy and innovation priorities. Further reading: How are GLP-1 drugs impacting spending on food and dietary supplements
Clinical trials (SURPASS programme) did not identify diverticulitis as a specific adverse event of concern
The study, published in Scientific Reports (Liu et al., 2025), systematically extracted and analyzed adverse drug reactions associated with concomitant administration of GLP-1 RAs and metformin for the first time using FAERS data spanning two decades (20042024), encompassing 48,214 adverse drug reaction reports
