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According to a 2013 review in Schizophrenia Research and Treatment , both typical and atypical antipsychotics can cause late or missed periods, with an increase in prolactin believed to be the primary reason

This animal safety profile is encouraging, but animal safety data does not establish that a compound is safe in humans

Competitive radioligand binding studies reveal nanomolar-range affinities, with the compound effectively displacing radiolabelled VEGF-A in receptor saturation experiments

Most randomized trials have been conducted in generally healthy populations, limiting generalizability to patients with specific diseases or conditions