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however, the clinical significance and durability of these effects remain under investigation

Although results of studies carried out to date do not confirm associations between GSTM1 , GSTT1 , and GSTP1 and epithelial ovarian cancer, the associations are biologically plausible because glutathione S -transferases metabolize exogenous and endogenous substances that may have a role in ovarian cancer carcinogenesis

Retatrutide is a triple agonist acting at GIP, GLP-1, and glucagon receptors, whereas semaglutide targets GLP-1 alone [4][3]