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Some practitioners theorize that BPC-157s effects on the flexor tendons passing through the carpal tunnel may indirectly benefit the median nerve by reducing tendon swelling and friction

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High ROS levels induce reversible oxidative PTMs on critical thiol residues of ETC proteins (for example S-glutathionylation or S-nitrosylation of Complex I subunits), impairing electron transport efficiency and increasing electron leakage that further amplifies ROS production and lowers m (58)

Limitations of Injectable BPC-157 Needle aversion: Some patients are uncomfortable with injections, leading to lower adherence