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The REDEFINE 3 cardiovascular outcomes trial which will take several years to complete is not a prerequisite for initial market authorisation for obesity treatment, but its results will likely be important for subsequent label expansion and for establishing the cardiovascular benefit profile that has proven so valuable for tirzepatide and semaglutide
This allows senescent cells to persist, contributing to chronic inflammation and age-related diseases (3)
[PubMed ID: 33348309].
Inflammation, redness, or sensitive skin
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