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A clinical trial showed that with Wegovy, the major adverse cardiovascular events (heart attack, stroke, cardiovascular death) can be reduced by 20% in specific patients with heart disease

Other trials will examine the effect of retatrutide on obstructive sleep apnea, chronic kidney disease, type 2 diabetes, major adverse cardiac events, and low back pain in addition to weight loss with expected readouts in 2026 and 2027

This is achieved through a multi-faceted pathway: Robust Clinical Review: Weve built a risk-based clinical criteria policy that evaluates the entire members profile such as their other medical conditions and past medications to ensure the right patients get the most appropriate medication for their unique situation

Celebrity & Media Attention Widespread media coverage and endorsements from high-profile figures have contributed to their popularity