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Microb Ecol
In environments where endogenous glutathione is severely depletedsuch as during a massive inflammatory flare, a viral cytokine storm, or an MCAS reactionthe free sulfhydryl group (-SH) on the NAC molecule allows it to act as a direct scavenger
In folic acid (FA)-induced AKI, Z-VAD-FMK, an inhibitor of apoptosis, could not reduce the damage to renal tubular epithelial cells, while the ferroptosis inhibitor Fer-1 effectively reduced oxidative stress and renal tubular cell death [136]
Radioprotection by glutathione esters and cysteamine in normal and glutathione-depleted mammalian cells
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