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Beyond psoriasis: a platform for inflammatory disease PEPITEM and its components are part of a wider research programme exploring their use in chronic inflammatory conditions such as rheumatoid arthritis, diabetes, and lupus
At the 12mg dose, participants averaged 24.2% body weight reduction over 48 weeks
ROS generated during oxidative stress can activate the IB kinase (IKK) complex, which phosphorylates IB proteins and marks them for ubiquitin-mediated degradation
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