semaglutide and colonoscopy prep GLP-1 agonists colonoscopy: What you need to know | University of Colorado Anschutz Cancer Center posted on the topic Health Rounds: No need to

GLP-1-related fatigue often presents as: Persistent low energy despite adequate sleep Mental fog or difficulty concentrating Physical weakness or feeling heavy Lack of motivation for usual activities Energy that comes and goes in waves Feeling more tired after eating (or not eating) This type of fatigue tends to feel different from ordinary tiredness and may fluctuate, especially around dose increases, significant dietary changes, or periods of rapid weight loss

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It is also wise to start with one new therapy at a time whenever possible so you can clearly understand what is helping, what is not, and what may be causing a reaction