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Both mutants likewise exhibited a similar downregulation of genes (Supplemental Figure 7A)

For example, a phase 2 trial showed that tirzepatide, a dual Gastric Inhibitory Polypeptide (GIP) and GLP-1 RA, significantly improved MASH

Clinical trial data: Participants eating large meals experienced nausea rates of 41% versus 22% for those eating small frequent meals

With proper medical supervision and a comprehensive management strategy, discontinuing Trulicity can be accomplished safely whilst maintaining adequate glycaemic control