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A prospective clinical study has demonstrated that ferroptosis levels showed considerable promise as a novel monitoring indicator and therapeutic target, as they play a critical role in predicting the healing rate of DFUs and assisting clinical treatment decisions [24]
Among the developed prodrugs, the lack of activity was confirmed only for D-glucose-conjugated prodrug of 7-chlorokynurenic acid (133, 134), glycosyl prodrugs of dopamine (135) and ibuprofen prodrugs (145)
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