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All these patients were complaining of menstrual irregularities and/or PCOS and had requested not to be treated with oral contraceptives
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Melatonin notably reduces glucocorticoid-triggered ferroptosis in BMSCs and prevents ferroptosis through the stimulation of the PI3K/AKT/mTOR signaling pathway, thereby preventing the onset of steroid-induced osteoporosis (SIOP) (43)
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