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However, the lipoatrophic diabetes observed in patients with lipodystrophies differs significantly from common type 2 diabetes in several regards, typically with significantly reduced adipose mass, dysregulation of adipose derived hormones including leptin and adiponectin, dyslipidaemia, more severe insulin resistance and significant hyperinsulinemia (2, 4, 6)

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The effects of LY2189265, a long-acting glucagon-like peptide-1 analogue, in a randomized, placebo-controlled, double-blind study of overweight/obese patients with type 2 diabetes: the EGO study