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Common downsides include nausea, reduced appetite, fatigue, and potential muscle loss if nutrition and training arent managed properly

The predominant complaints were nausea, vomiting and diarrhoea

However, translating these findings into human applications is far from straightforward

We hypothesised that greater weight loss by co-activation of GLP-1R/NPY2R would have a greater effect on post-stroke recovery than semaglutide monotherapy