In patients with obesity and type 2 diabetes, carnitine supplementation improves insulin-induced glucose utilization and increases fatty acid oxidation rates
Both compounds have long half-lives that maintain steady-state levels when dosed on a consistent schedule
They can disrupt the body's natural processes in many ways: mitochondrial function, stress hormone production, brain function, adrenal function, thyroid T4/T3 conversion, immune system regulation, virus susceptibility, reduced glutathione stores, increased inflammation, and reduced detoxification
Medicare and Medicaid coverage limitations create substantial barriers for patients requiring medication intervention, though recent policy proposals may improve access for millions of beneficiaries