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The results showed that after transfection with siSTAT3, GHK-Cu treatment showed a synergistic effect on the inhibition of inflammatory factors (Figures 8AE)

This is driven by expanding type 2 diabetes adoption, wide regulatory approvals, and strong clinical effectiveness

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It showed also anti-inflammatory properties by downregulating the expression of pro-inflammatory mediators, such as iNOS, COX-2, and TNF-, along with inhibition of the NF-B signaling pathway [75]