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They stimulate the pituitary gland to produce and release its own GH in a pulsatile, physiologic pattern
They stimulate GH as well as other hormones such as ACTH and cortisol
Its triple-agonist mechanism targeting GLP-1, GIP, and glucagon simultaneously is genuinely novel, and the liver fat reduction data (82% at 24 weeks, per Sanyal et al., Nature Medicine 2024) is in a class of its own
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