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Therapeutic & Clinical Implications 1
Sharon Barr, executive vice president, biopharmaceuticals R&D at AstraZeneca, said, Building on the promising Phase I clinical data generated by Eccogene, we believe this oral GLP-1RA molecule could offer alternatives to current injectable therapies both as a potential monotherapy as well as in combination for cardiometabolic diseases such as type 2 diabetes, as well as for obesity
Participants who started too high or escalated too quickly in clinical trials experienced nearly double the rate of nausea and vomiting compared to those who followed the gradual protocol
The animal science is real, but calling it 'proven' is a stretch when 99.7% of the research is in rats
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