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NADPH, in turn, is the electron donor that glutathione reductase uses to regenerate oxidized glutathione (GSSG) back to its active reduced form (GSH)
Lastly, to evaluate the robustness of the associations detected, we additionally included data collected from NESDA subjects still available at 6-year follow-up by pooling all observations (N = 4141) in a unified mixed model with two random factors (one for the family effect and one for the repeated observations from the same subject over time)
[Phosphorylation and activation of glutathione peroxidase and glutathione-S-transferase by cAMP-dependent protein kinase]
Circulation research
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