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The methods range from dietary or intravenous administration of NAD + and precursors to inhibition of NAD + -consuming enzymes with small molecules, to activation of the NAD + synthesis enzymes
NF-kappaB: A key role in inflammatory diseases

Oxidative stress (formulated in Harman's free radical theory of aging) is also thought to contribute to the process

A reduction of saturated fats & high carb content is also advised to be followed in the days immediately after treatment
