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discovered that Guhan Yangsheng Jing, a traditional Chinese patent medicine primarily composed of Polygonatum sibiricum , Epimedium , and Lycium barbarum , ameliorates reproductive damage in diabetic male rats by upregulating the Nrf2/HO-1 pathway to alleviate oxidative stress and ferroptosis [179]
E.DiekmannF.StampflA
But the results were very short lived
10.1007/s00239-008-9097-1 Summary Keywords cross-strand disulfide, forbidden disulfide, redox-active disulfide, exaptation, disulfide evolution, CD4 evolution, AKT evolution, post-translational cysteine modification Citation Mohanasundaram KA, Haworth NL, Grover MP, Crowley TM, Goscinski A and Wouters MA (2015) Potential role of glutathione in evolution of thiol-based redox signaling sites in proteins
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