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Use different areas of the abdomen, thighs, or upper arms each week, avoiding the same exact spot for at least 4 weeks
The matrix below pairs the five most common 2026 research objectives with the compound whose published Phase 2/3 data most directly answers it, anchored to SURMOUNT-1 (tirzepatide), STEP 1 (semaglutide), and Jastreboff et al
How semaglutide works: the science behind the protocol Understanding the mechanism helps explain why accurate dosing matters so much
Increase hydration: Drinking more water and clear fluids can help replenish lost fluids and prevent dehydration
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