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PMID: 9329386
The ICR mice were used to establish an AD model in vivo , while PC12 cells (treated with A25-35) were used to build an in vitro AD model
Nakamura, Y., Hirano, S., Suzuki, K
Low concentrations (5 nM) of HDACi Dactinostat and Panobinostat can significantly enhance the proliferation of primary natural killer cells (pNK cells) induced by IL-2 through the JAK-STAT signaling pathway ( 2.6 Effect of HDACi on dendritic cells Dendritic cells (DCs) are key antigen-presenting cells in the immune system, playing a critical role in antitumor immunity ( 3 Joint application of HDACi HDAC inhibitors significantly enhance the antitumor efficacy of immune checkpoint inhibitors, CAR-T therapy, and chemotherapy through epigenetic remodeling
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