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The deficit is established and sustainable
In a 2021 study , Ozempic lowered A1C by 1.6% by 30 weeks and Rybelsus by 1.4% over 26 weeks
Jumping to a high dose without the adaptation period dramatically increases the risk of severe nausea, vomiting, and diarrhea
However, they can jump-start progress and make it easier for patients to adopt healthier lifestyles by reducing appetite and improving energy, which can be a virtuous cycle
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