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Despite the preclinical promise shown by pharmacological agents that target ferroptosis-such as inducers like erastin and RSL3, and inhibitors like fer-1-their application in clinical settings encounters difficulties, which include unintended effects and restricted tissue specificity [2, 99]

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There is also evidence that semen contains cytokines and prostaglandins that affect the female reproductive tract

Regarding the improvement of insulin sensitivity, omega-3 fatty acids inhibit the activation of nuclear factor kappa B (NF-kB), which reduces the production of pro-inflammatory cytokines and helps reverse insulin resistance