This is a joint Collection across Communications Medicine , Nature Mental Health , Nature Metabolism , Nature Medicin e, Nature Communications , and npj Metabolic Health and Disease , and all submissions will follow the standard editorial and peerreview processes of the participating journals.
Inactivation of the medial prefrontal cortex of the rat impairs strategy set-shifting, but not reversal learning, using a novel, automated procedure
When the patient is on one medication and the pain is still unbearable, the second medicine may be started at a low dose and titrated up as the patient tolerates and as the pain decreases
Combined with strong lifestyle capacity, you have reasonable chance at maintaining significant portion of loss off medication