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Investigation of the mechanisms underlying the beneficial metabolic effects of multi-agonist therapies, conducted in PWA mice, as a genuine model for the metabolic alterations of PCOS 36 , revealed a predominant action in terms of suppression of food intake, with negligible effects in terms of energy expenditure, thermogenic function or locomotor activity
And that was it."
However, these mechanisms remain speculative in human RA and require validation through dedicated clinical trials
Even for those taking them, the weight loss effect is not guaranteed
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